Irbesartan and Hydrochlorothiazide tablet
What is this medicine?
IRBESARTAN; HYDROCHLOROTHIAZIDE is a combination of a drug that relaxes blood vessels and a diuretic. It is used to treat high blood pressure.
What should my health care professional know before I take this medicine?
They need to know if you have any of these conditions:
decreased urine
if you are on a special diet, like a low salt diet
immune system problems, like lupus
kidney disease
liver disease
an unusual or allergic reaction to irbesartan, hydrochlorothiazide, sulfa drugs, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
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Possible food and drug interactions when taking Avalide
Alcohol may increase the effects of Avalide. Use it with caution.
If Avalide is taken with certain other drugs the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Avalide with the following:
Adrenocorticotropic hormone (ACTH)
Barbiturates such as phenobarbital and secobarbital
Cholestyramine
Colestipol
Insulin
Lithium
Narcotic painkillers such as acetaminophen, codeine phosphate, meperidine hydrochloride, and oxycodone hydrochloride
Nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen sodium
Other blood pressure medications such as atenolol and nifedipine
Oral diabetes drugs such as chlorpropamide, glipizide, and glyburide
Steroids such as prednisone
Special information if you are pregnant or breastfeeding
When used in the second and third trimesters of pregnancy, Avalide can cause injury and even death to the unborn child. Stop taking Avalide as soon as you know you are pregnant. If you know you are pregnant or plan to become pregnant, tell your doctor immediately.
Avalide appears in breast milk and can affect the nursing infant. If Avalide is essential to your health, your doctor may advise you to stop breastfeeding while you are taking Avalide.
Recommended dosage for Avalide
Avalide tablets come in two strengths:
150 milligrams irbesartan with 12.5 milligrams hydrochlorothiazide
300 milligrams irbesartan with 12.5 milligrams hydrochlorothiazide
ADULTS
The usual starting dose of Avalide is 1 lower-strength tablet daily.
It will take 2 to 4 weeks for Avalide to reach its maximum effectiveness. If your blood pressure does not respond to the initial dosage, your doctor may increase the dosage to 1 higher-strength tablet or 2 lower-strength tablets taken once a day.
Overdosage
Any medication taken in excess can have serious consequences. Information on Avalide overdosage is limited, but extremely low blood pressure and an unusually rapid or slow heartbeat are likely signs of an overdose. Other signs may include dry mouth, excessive thirst, muscle cramps, weakness, restlessness, confusion, and nausea. If you suspect an overdose, seek medical attention immediately.
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